Technical FAQ · Question 2
Why HVAC Systems Need Microbial Contamination Control — and How VanTsteri Helps
Assessment, disinfection and verification for the system and its application.
1. Why contamination can accumulate
HVAC systems in pharmaceutical production, food facilities and laboratories continuously handle and distribute air. Airborne microorganisms, dust and other particles can be captured or deposited on filters, inside air-handling units and in ductwork. Over time, accumulated dust and persistent moisture can create conditions that allow microorganisms to remain or grow, increasing environmental contamination risk.
2. What to inspect when problems recur
Assessment should consider the air-handling unit, filters, coils, condensate pans and ductwork, together with condensation, drainage problems and maintenance abnormalities. Repeated environmental findings warrant investigation into possible sources and affected system locations.
If your facility has recurring contamination concerns, VanTsteri can help discuss the available evidence and the investigation needed.
3. Establish a periodic monitoring and review procedure
A planned procedure should bring together periodic monitoring, assessment, disinfection and verification. It should identify the basis for inspections, how outcomes will be evaluated and when they will be reviewed.
The plan should reflect the facility’s use, contamination evidence, monitoring trends and applicable requirements. Changes to the system or abnormal findings should prompt reassessment of the relevant scope and approach.
4. Assess the system before choosing the work
VanTsteri works with facility, engineering and quality teams to review system structure, filtration and zoning, maintenance records and contamination evidence. Planning also considers access, materials and the impact of work on the facility.
In an existing system with high-efficiency filtration, dismantling components, creating access openings or extensive cleaning can introduce engineering risks. The need for cleaning and its extent should therefore follow assessment of the particular system. Where contamination, deposits or faults affect the proposed treatment, appropriate cleaning or repairs should be arranged.
5. Follow assessment → disinfection → verification
The main process is assessment, disinfection and verification. Assessment establishes the targets and treatment scope, together with any necessary preparation. VanTsteri then supports equipment selection and professional on-site implementation, followed by evaluation against agreed criteria that meet applicable requirements.
Extensive dismantling and cleaning are not a fixed prerequisite for every project. Necessary preparation should be determined from the findings and the work required.
6. Evaluate room and HVAC coverage separately
A room treatment does not automatically establish that internal HVAC components were included or effectively treated. Ductwork, coils and condensate pans have their own structures and hygiene conditions. Likewise, an internal HVAC treatment result does not automatically establish the result for the room.
Each treatment scope needs its own coverage assessment and appropriate evidence of effectiveness.
7. How VanTsteri supports implementation and evaluation
VanTsteri brings together contamination investigation, equipment, professional implementation and evaluation. Following a suitability assessment, KINO SUBZERO can be considered in conjunction with the existing HVAC system.
Monitoring at multiple locations in the room and relevant system positions can help assess concentration distribution and changes during treatment. These readings should be considered alongside independent effectiveness evidence appropriate to the agreed targets. Concentration readings alone do not demonstrate disinfection effectiveness.

8. Discuss your system with VanTsteri
Provide the facility’s use, system drawings, filtration configuration, maintenance history, monitoring data and the problem you are seeing. These details help define the scope, implementation arrangements and evaluation approach.